Death, Aging, Rejuvenation (Part 4)

Aleksandr Kavokin, MD,PhD
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Biological clock
Obviously you need biological clock to time and alarm the point when you need to die and when you need to age. Aging is the same death as in those one-day butterflies, but a little bit prolonged one. Not immediate kill but gradual shut down of protection mechanisms – immunological, genetical repair, and just other necessary functions of proliferation. As soon as those functions turned off – an organism starts to deteriorate and wear off.
Interesting that our organism is not a static thing. We probably replace all molecules in our body within relatively short period of time. Obviously water is replaced completely every couple months. Water is 60% of our body. Other molecules are replaced as well. Thus, human being is just some unstable chemical organisation around genetical information. Molecules swirl and disappear like crazy. DNA in cells maybe is not changed so fast, but the cells themselves change quickly in most of cases. There is no need to age just because of wearing.
Biological clocks are necessary and there is no doubt they exist.
The theories of aging that consider death as a sequence of events caused by external causes – like oxidations and accumulation of genetical errors should anyway include the idea of Internal Biological Clock as well. Simple example is menopause in women. Somewhere at 40-55 all women undergo menopause. Unavoidable. Though there were reports of childbirth at 60 yo but considering one chance in billions, it is just a joke. Males have their equivalents too. All people after certain age change their immunological, hormonal, metabolic levels and so on. Majority of organs decrease their function . Thymus involute. Fat cells overgrow others, muscle cells degenerate etc. The same happens to all other multicellular animals and plants.
Now the real question: Is it possible to break the biological clock or at least slow down and rejuvenate?
Possible methods of rejuvenation.
1. Telomeres lengthening and other genes regulation.
Several genes that might play role in aging described recently. Telomerase encoding genes are the most discussed. In theory, if we lengthen the telomeres (these are the ends of chromosomes that are shortened with each division by very interesting mechanism), we could overcome cell tendency to lose ability for proliferation. Hence, we have “immortal cells”. Hence, immortality or at least longevity is reached – cells divide indefinitely and repair organism. Basically, to restore telomeres length we need to activate production of or to introduce into the cell an enzyme named telomerase. To reach each cell in the body we would use viral vectors or smallRNA. Working with virus production and then cell transduction I would say it is difficult, very difficult. There are too many obstacles to use them efficiently. SmallRNAs would be more promising. In any case, when you go from theory to practice problems rise exponentially. Biggest question: will it work? Immortal cell (cell which is able to divide indefinitely) does not mean immortal body. One of the outcomes would be uncontrollable cell growth and, hence, cancer. Actually scenists discuss telomeres mostly in connection with cancer. They are very cautious saying about the rejuvenation. Mass media extrapolates the findings to possibility of longevity and further rejuvenation.
My guess would be that telomeres are some of the “final cogwheels” in the Internal biological clock. It is useful to divide the clock on intracellular and whole body levels just for understanding. But in reality the levels are not separable, they continue one into another. It is easy to understand that intracellular production of any protein, any enzyme depends on transmembrane regulation. Hormones activate receptors that activate DNA transcription and protein production. Other genes that play role in cellular aging are described recently as well. I do not know how to use this method at present time
2. Hormone replacement.
When I studied in med school, several time I met mentions about hormonal side effects that cause a person to look much younger. Well known for example are: If a woman in menopause suddenly resumes menstrual cycles and looks younger than her age, we might suspect an ovarian Tumour producing excess of estrogen. If a person has thyrotoxicosis – excess of hormone thyroxine – he/she loses weight and looks much younger Persons with manic phases of bipolar disorder look younger, more energetic. Certain hormones – corticosteroids for example – might be increased or decreased in elderly. Couples that look younger were shown to have increased level of sexual relationships. Again, that supposedly should significantly change the hormonal levels.
If we give a person some of those synthetic hormones – estrogen, thyroxine – we can sometime reproduce the younger looks.
It is not the same as plastic surgery or skin creams and massages. It invigorates whole body. Skin as well. There is heavy price – recent debates are waxing and waning – if estrogen replacement increases or decreases risks of cancers (uterine, breast, ovarian etc.) Thyroxine excess takes heavy tall on cardiovascular system. Psychiatric disorders (mania for example) was linked to ceratin changes in neurotransmitter levels. Certain psycho tropic drugs change the ratios. Supposedly they can be employed for rejuvenation. Unfortunately, you would rather receive a psychosis than younger look.
On internet you can find massive information about hormones that rejuvenate you. I saw some websites that list practically any major hormone: read more

Death, Aging, Rejuvenation (Part 3)

Aleksandr Kavokin, MD,PhD
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Aging
How did aging appeared?
If mechanism of Death was chosen by evolution, how was aging chosen?
Why for example at certain age animals do not die instantly and just give the room for the next generation. Nurturing is one explanation at least for human society.
But lets say new generation of young adults already reached puberty . Why would not old generation die in an instant. Why do they age?
Actually there is nothing impossible. Some butterflies grow couple years, mate, produce new generation and die in one day. Some plants live 1 year, some live 2 years and then invariably die. Some live 1000 years. Lemmings, having overgrowth of population, just go and massively commit suicide in the sea. No questioned asked.
Why aging in other animals take several years?
It might be selected by cut-throat evolution during another catastrophe.
A relatively mild Cataclysm happened in the same time when all adults died programmed to do so. Older animals would survive the disaster. But they died instantly from internal timer. Younger generation did not tolerate the mishap.
All species that did it – just disappeared. Younger animals were not adapted to new conditions. Only animals with mechanism of aging were selected. Maybe the aged animals are not so good as younger ones. They already slightly deteriorated. But it is better than nothing.
Anyway. It makes sense why Death and Aging were selected during the Evolution.
– continued in Part 4
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Death, Aging, Rejuvenation (Part 2)

Aleksandr Kavokin, MD,PhD
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Death
Death. Why it happens? Why do we die? Why do animals die? Why do plants die? What is the need of this? In my opinion mechanism of death was selected during Evolution.
From the position of Darwin’s theory of Natural Selection everything, that benefits survival of species and gives advantage in Natural Selection, is preserved in following generations.
Improvements were often left unchanged from the moment of life appearance. Though there could be other ways, certain mechanisms were accidentally selected. These improvements are reproduced in the genome of more complex species. Billions of years ago, according to the theory of evolution, chemicals randomly organized themselves into a self-replicating molecule.
Lightings and UV-radiation helped to create first organic molecules. This phenomenon is reproducible in a lab. The experiments were described in 1950-60.
First self-replicating molecules were probably RNA. First enzymes were probably RNA – enzymes. Then proteins, DNA and more complex lipid molecules and polysaccharide came to the scene.
Death as it is did not exist at the stage of Primeval Soup . Sure some organic molecules were destroyed , some new created. But in general it was still that swirling and bubbling primary broth – quasi alive in our understanding as a mixture of biochemical reactions.
Everything in the evolution was build from the previous blocks selected sometime by accident.
Appearance of lipid membranes allows to compartmentalize the primary broth and create first cells.
At the cellular stage we could already talk about the Death. Cell is destroyed, membrane is broken, everything leaked out. This is the Death.
Content of cell inside lipid membrane is irradiated. Process of crazy molecular swirling is messed up by free radicals irreversibly. This is also signs of Death.
Yet at the cellular stage we cannot talk about Aging. Death at this stage is accidental, not programed.
Organic molecules may age (oxidation, conjugation, etc.) and cell would die. But damaged molecule are repaired or synthesized fresh usually. Hence, no good reason for a single cell organism to age. Irreparable damage from external cause leads to Death, not Aging. This is accidental death. For multicellular organisms, there is a parental organism that ages and eventually dies after next generation is born. For mono-cellular organism, there is parental organism that divides and becomes the next generation. There is no Aging leading to death of parental organism.
Mono-cellular organisms are practically immortal in a right environment.
Mechanism of division was selected during evolution. Cell has volume (3-D). Surface membrane is measured in square units (2-D). Growing beyond limits cause inadequate supply of nutrition from environment. Division solves the problem.
Microbes, bacteria are immortal. Some divide every 20 minutes. In a an hour they multiply 8 times.
Tumour cells divide slower. They are eukaryote. Most aggressive divide once a day. There is no need for Aging.
They would die if you do not feed them. They die when you kill them with undiluted bleach in a flask. Otherwise they grow unstoppable. No aging.
Multicellular organism supposedly has several control mechanisms to prevent excessive growth and division, to kill an extra cell. Apoptosis, programmed death, is used.
Cancer cells often loose the control mechanisms.
A scientist from Yale once pointed out to me that we can not say these cells are immortal. Maybe they divide and parental cell dies. Indeed. We do not follow the fate of every individual cell during experiments. They should give more children cells than parental cells die. Otherwise there would not be the multiplication. It is a possible scenario. We do not follow the fate of individual bacteria as well. Maybe they actually undergo aging.
From the other hand some experiments suggest that new cells contain roughly half of the parent cell after division. So it is not Death or Aging. Next generations contain 1/4, 1/8, 1/16 and so on of the parent cell. Any mechanism that is more complex than simple division would cause disadvantage in evolution and would be quickly eliminated. On the level of mono-cellular organism neither Aging nor Apoptosis make a lot of sense. Though Nature often have hidden reasons.
Flick’s phenomenon and telomeres shortening make sense for a multicellular organism. Cells of multicellular organism do age. They stop dividing after 70 divisions or so.
A multi-cell organism has clear cut advantage over a mono-cell.
Why would mechanism of Death selected for multicellular organisms? Scenario could be the following.
Big organism have more advantages compare to smaller one – stability, protection, etc. There are not so many natural enemies for whale or elephant because of their size. Large animals could be brought down by bacteria, viruses, small parasites, and lack of available food. Rare predator attack whale or elephant.
No wonder that evolution was going into the direction of bigger animals – just look at giant bones of dinosaurs and you will feel some appreciation.
Millions years ago not only Dinosaurs but also insects or crustacean were enormous. Cockroaches, spiders or dragon flies with size of one metre (3 feet). Going back in time we find shells of enormous molluscs. Many things imply that bigger animal with unstoppable growth have a lot of advantages compare to small ones. New species often evolve in their size. An example is growth acceleration in humans. Females prefer taller mates that lead to taller children. Shorter plants usually cannot compete with the taller forms in the wild. A short mutant in a patch of tall plants would be shaded out
Mechanism of reproduction was also selected during the evolution. Any new animal, be it a mouse or a human, starts life as a single cell. That cell differentiates and develops into the complete animal. It assures that a rare advantageous variant sequence of DNA will be rapidly propagated by natural selection. It is much easier to reproduce and maybe get some new genes or favourable mutations starting from a single cell than starting from a whole multicellular organism. Functions of most genes will have been optimized by random point mutation and selection in any given species. Signalling between cells during the development process ensure that everything ends up in the right place. Tiny changes in these Signalling processes can have very large effects on the resulting animal. Genome, with at most forty-sixty thousands genes, is able to specify the creation of a human body containing trillions of cells, billions of carefully wired neurons and hundreds of different cell types all amazingly sculpted into organs as diverse as the liver and the brain. This is why mechanism of proliferation of fertilized oocytes was selected.
Hence, having younger (smaller) and older (bigger) animals make sense.
But there is the problem: adult animals (or plants) consume all the nutrition around and there is not much left for next generation.
Then it is why mechanism of Death was selected as a mean for next generation to establish.
Imagine the following:
First, mechanism of proliferation was selected . If mono-cellular organism does not have mechanism of reproduction it does not produce offspring with possible favourable mutations. Let say there are primitive bacteria spontaneously created in primeval soup. Just few of them. They consume nutrition, they live happily, practically immortal but they do not divide. Then set of enzymes appeared during mutations. The set allows bacteria to split. Synthesis of the new set is disadvantageous. It requires additional energy and nutrition. But advantage of splitting allows new mutants immediately overgrow non-proliferating cells. Selection is really cutthroat.
Bacteria growing in a tube represent mini evolution. Any bacteria that fit for the environment are also selected on the ground of simplicity. In a toxic environment (antibiotics) mutant bacteria having a new mechanism of neutralisation would survive. But the more simple bacteria will eventually overgrow complicated ones. Unless complication gives big advantage that outweigh the benefits of simplicity. Another example: HIV virus is very complex compare to some other viruses. But because of the complexity it evades immune response. This is why it is so successful. For humans there was some discussion that hernias are direct problem of erect posture. So erect posture leads to disadvantage. From the other hand erect posture frees the hand, that allows to produce the tools and this gives huge advantage in the survival in natural world by creating possibility to adapt to virtually any condition.
All high animals have just 4 extremities. Obviously it is enough in cutthroat environment. Growing additional couple of extremities will consume much more resources and take much more time, not giving big advantage in speed or protection of an animal. Thus, danger of losing one of the limb is not so big as the danger to not proliferate fast enough.
Bilateral design of majority of animals was chosen at the level of primitive species. Though lower multicellular organisms may have 3-side symmetry or 5-side symmetry like sea stars. Often something chosen in the selection becomes building blocks for higher species. Maybe 5-side symmetrical tiger would be possible but it requires intermediate chain.
The same is true for the mechanism of Death. Once chosen, it is replicated in all higher organisms. It should give an advantage in ultimate species survival. Otherwise it loses sense and species would be wiped out.
So, what is advantage for Death?
Immortal and childless animals are growing and growing. Mutations lead to species producing offsprings. They have disadvantage of been more complex. But advantage of proliferating animals is occupation of vaster areas. They displace immortal and childless species. Now, if proliferating animals are immortal they do not give offsprings enough space or food. Next steps of mutation brought mechanism of programmed death at certain age.
Let consider situation when out of two species one is immortal and producing offsprings, other is mortal with offspring production as well. Mortality looks like an obvious disadvantage in stable environment. Adult organism are more powerful and more protected compare to juvenile.
However, next catastrophe will wipe out all the species altogether. Only some mutants can adopt to new environment. But “mutant” for a multicellular organism imply that the mutation happened when the organism had only one cell (the stage of fertilized oocyte for example). Otherwise it needs precisely the same mutations on the level of several cells – infinitely impossible event.
Thus, any species that had the mechanism to allow next generation to flourish (mechanism of programmed Death) will have advantage. They produce more offspring than immortal species. Death of parents spares the space and nutrition. Immortals can die form accidents only. It is too long for children to expect a vacancy.
Then, having more offspring automatically means having more mutations (by mere number of events). Having more mutations means more probability for adaptation to the new environment.
Immortal multicellular organisms, even if they existed in the past, were quickly wiped out by accidents and overgrown by mortal multicellular organisms.
Again all this is just a hypothesis.
– continued in Part 3
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Death, Aging, Rejuvenation (Part 1)

Aleksandr Kavokin, MD,PhD
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I would like to raise a question: Is Rejuvenation possible and how to approach it? This is just my own opinion about possible procedures. I used certain techniques based on a theory. As strange as it sounds some of those techniques and procedures might actually worked.
There are several hundreds theories of aging. New and old ones. Different authors classify them differently.
I would divide all those theories into 2 groups :
1. Theories of Deterioration from external cause. “Wear and tear”. Theory of free radicals damage is most fashionable at present time. Antioxidants are considered a cure. Benefits of caloric restriction are often explained by that theory. The theory has good objective support in scientific literature. Other theories of this group included changes of bacteria in the gut, radiation and accumulation of mutations during life of an individual, etc. – many more of those theories were discussed in the XX century. 2. Internal clock – theories.
I would divide the “internal clock” theories into 2 more subgroups: 1. Internal clock on the level of cell. Telomeres shortening is the most discussed in literature at present. 2. Internal clock on the level of organism. Growth hormone changes was a recent example of discussion.
Authors are usually very cautious and objective in scientific literature. Telomeres are usually discussed in connection with “immortal” cancer cells. Caloric restriction is discussed as a mean of longevity (not rejuvenation per se). Level of growth hormone (GH) or insulin-like growth factor drops in aged persons.
Mass media speculates wider: telomeres restoration – possible immortal life, growth hormone will rejuvenate you, etc.
Original scientific studies usually do not speculate about this. In no way for example drop of GH level in elderly means that just giving it back will make you young again.
Scientific literature rarely discuss “Rejuvenation” as it is. Authors mostly talk about “longevity”. This is very different story. Longevity in a wheelchair is very distinct from a youth playing soccer. One proven method to reach longevity is caloric restriction. Often they say it is the only proven technique. Using antioxidants as a method to prolong life is in the same category. To put simple, the Theory says: nutrition produce products of oxidation – peroxides, etc. These products damage DNA, proteins, etc. Cell ages. Caloric restriction switches metabolic pathways. There are less free radicals. Hence longevity. Antioxidants work in similar way – they remove free radicals. Another speculation is that caloric restriction starting at young age delays reproductive age in animals and this slows down biological clocks and prolongs life until an environment with high nutrition supply is found. Animals look small and undeveloped.
Caloric restriction significantly (25%-100% and more) prolonged life in worms, flies, spiders, rats, mice, etc. Experiments on monkeys and humans are under way and will take decades.
Well, it is all good in experiments and theories. Some argue: why in this case prisoners of concentration camps do not live longer. Another example came from “Scientific American” – a person had caloric restriction of something 20 years or more – no effect – he just looks like very thin undernourished person of 50 years. Examples of opposite opinion also exist (tribes or groups with low food consumption or high antioxidants consumption have more centenarians than general population). Maybe you really need to start at 10 years of age, look malnourished and weak for the whole life and live to 100 years, getting to your puberty at 25. Antioxidants also bring many controversy. Vitamin E did not show many benefits though it was a big hope for prevention of many diseases of old age. And so on. Today there are big trials that disprove the theory. Tomorrow – great experiments that confirm the theory, at least partially. Many big trials and experiments are published in leading journals – Science, Nature, PNAS, New England JM, JAMA, etc.
One bias for caloric restriction experiment in my opinion is following. Rats live in cage 30cmX60cm for their whole life. There are at least five rats or 20 mice. They live couple years and die. During the experiments they are celebrities when they live 5 years – some lucky ones. The Food is a balanced mixture of nutrition. Caloric restriction is – 60% of their regular meal. They practically don’t move – there is no space in cage. Mostly they sleep whole day. Sometime they fight and mate. They live in those conditions at Yale, at Med U of South Carolina, at Russian State Medical University and I think everywhere else. To compare our fellow humans we would place 10 people on area of 20 square metres (200 sq. feet) for 50 years in a row, feeding them with what they want but all the same – let say junk food from McDonalds.
I remember my cat (who was partially wild) stole meat and ate until it started to vomit. He repeated it many times when he was able to steal some steak or whatever. The same happens in wild – lions have maybe one successful hunt out of ten. When they catch a prey, they eat like crazy. Much more than they can digest at the moment. So it looks like there is an instinct. Eat as much as possible. This is not a joke – 60% of people in western countries are overweight. Abundant high calorie food and lack of activity. It does not seem that for these people any internal mechanism restricts food consumption. Applying this back to rats, we can see that what is considered normal consumption – “ad lib” – maybe actually big overfeeding of the animals in these cages. In this case 60% of caloric restriction would be just what rats need, just what the calories they spend in lazy, uneventful daily life. So called “control”, “normal” rats – that fed as they usually fed might be compared for fat overweight humans. They consume junk food. They prone to the bunch of diseases of obesity and low activity. Heart diseases, strokes, variety of cancers, arthritis, etc. In this case all the hype about caloric restriction would just be brought to the business of mere balancing diet and activity in so called “calorie-restricted animals”. I haven’t seen any discussion of this problem. I might be wrong. This is why I use caloric restriction for myself. I did not work with worms and spiders. But my guess would be that they all are also in artificial standardized conditions. “Control” worms might be also overfed. To put rats into bigger cages (to increase activity in control group and balance calories and catabolism) would be incredibly expensive. Even at present conditions because of “animal lovers” and bunch of other regulations and considerations (e.g. sterile conditions), the price of animal housing is sky-high.
You would say animals in wild would live longer because they balance activity and consumption. Well, recently I read that life span of animals in wild is shorter than animals in captivity. Correct me if I am wrong: pandas live 15-20 years in nature and 20-30 in zoos, bears 20-25 in nature and 30-40 in captivity. Civilization has certain benefits – vaccinations, good medical care, more or less good hygiene. So just moving into wild conditions wouldn’t make you younger or allow to live longer.
Now, to discuss rejuvenation procedures, I would need to talk about aging first. In this case Rejuvenation could be considered as reversal of aging (deterioration). Longevity is different story – it is prolonged life span. Rejuvenation supposedly should lead to longevity. But longevity is not equal to Rejuvenation. Aging leads to Death eventually. It is easier to discuss from that end.
All written here is just plain speculation, take it with a grain of salt.
– continued in Part 2
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Dealing with Workplace Stress

Trevor Dumbleton
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One of the hardest forms of stress to avoid is workplace stress. After all, you need to go to work and there are plenty of things to worry about once you get there. However, that does not mean that workplace stress is unavoidable. Just like other kinds of stress, there are ways to manage workplace stress and there are ways to avoid it. Maybe you cannot avoid it entirely, but that is no reason not to try.
Workplace stress usually takes the form of everything needing to get done right now. You know the situation, there are a dozen things on your plate and they all need attention, but there are only so many hours in the day and you cannot attend to everything all at once. On top of that, the boss is breathing down your neck, asking you where the report/plan/program is and he also has a pile of other tasks for you once you finish that. It is a never-ending cycle, but it can be managed.
The first thing you need to do to avoid workplace stress is to focus on one task at a time. Do not try to multi-task, as it jars your system. Switching gears between projects does make demands on your brain and it takes a moment to change your thoughts from one place to another. Instead, if you focus on one project, you can keep your thoughts and energy in one place, preventing you from having to shift gears too often.
However, the big problem with trying to keep your focus is your coworkers. They will always be asking you for a quick minute or they will want you to answer their question, or they will want you to come over and help them on something. Try to deflect these as much as possible, as these can distract your focus. Thus, you must learn to say, “no.” This is a highly effective word, though you may want to change it to, “No, not right now,” or, “As soon as I am done with this.” These little phrases can at least buy you some time to finish what you are doing, then switch comfortably to the needs of your coworkers.
There is another cause of workplace stress that can also cause you all manner of difficulty and that is when your concentration runs out. Oftentimes, you may find yourself focusing on the same page or the same computer screen for minutes at a time and you still have no idea what it is supposed to mean. This is not good, as it means that you are not being effective, your brain has shut down and the deadline is looming over you and you just need to get through this. Your best plan at this point is to walk away from your desk. Get up, get a cup of coffee (but not too often, as caffeine can heighten stress), go to the bathroom, anything. Walk the corridors for a minute or two and clear the cobwebs. This is highly effective both for ensuring that you are getting work done and for keeping workplace stress to a minimum.
Another way to prevent workplace stress is to learn some desk exercises. These can be simply squeezing a stress ball, or performing a few stretches while you are at your desk. By working your muscles at your desk, you can improve your circulation and help your keep alert and aware at work. Obviously, you are not going to get a full body workout while you are pecking at a keyboard, but it can help you at least keep your mind focused.
Finally, while you are at work you should examine your environment to see if it is right for you. How is the noise level? Is your desk set up properly? Are you comfortable? Is everything set up so that it is ergonomically correct? Your body needs to be comfortable if you want to work without distraction and distractions can lead to workplace stress. Thus, your work area needs to be set up for you. Take care of the little things around you and you will be able to work confidently and work well.
Workplace stress is, in many ways, part of working. However, by managing workplace stress properly, you can at least keep it to a minimum. And by doing that, work will be much more pleasant and you will be much more productive. So take care of yourself and the area around you and workplace stress will not control your day.
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Dealing With The Emotional Scars Of Acne

Peter Vine
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category:health
article:

Acne is widely accepted, as no longer, being a physical problem. There can be deep emotional issues that arise from acne irrespective of the severity of the condition. Over the last 5 years or so, doctors have started to look at some of the more serious psychological effects of acne. Some of the most problematic psychological effects of acne include: read more

Dealing With The After-Effects Of Acne

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Acne can sometimes leave scars behind if not treated properly. These scars can often be difficult to remove, with various forms of facial surgery being a typical option. In most cases, the scars can be prevented by just taking a few measures while the acne is still present, such as using the medication properly.

infection, side effect, inflammation, surgery

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Acne, unlike your typical infection, is not something that’s over and done with if you manage to make it go away. You still have to deal with the after-effects left behind by the problem. Acne scarring is one of the most common problems encountered during the post-infection stage. If not treated properly, acne can leave physical marks. Acne scarring, with the social stigma that it tends to generate, may end up becoming an even bigger problem than the acne that caused it. No wonder, some people actually see depression as one of the more serious effects of this kind of skin problem. read more

Dealing with Stress Due to Sleep Deprivation

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The article talks about the the ill-effects of sleep deprivation. Individuals who lack sleep may experience stress, fatigue, and other adverse effects to one’s health. In addition to these negative physical effects, recent studies suggest that lack of sleep may heighten the risk or prevalence of adolescents who take up smoking and consume alcoholic beverages.

cigarette smoking, sleep aid, stress

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Lack of sleep may throw the body’s system off balance. It is one of the factors that may contribute to stress and fatigue. In the long run, lack of sleep hampers a person’s emotional well-being, mental abilities, productivity, and performance. read more

Dealing With Stress and Anxiety the Natural Way

Colleen Palati
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If you have ever had an anxiety attack or suspect that you may suffer from a general anxiety disorder, this information will be quite helpful to you. 30 million Americans have been diagnosed with general anxiety disorders, including panic disorders, phobias and post-traumatic stress disorders. Another 35 million people with anxiety suffer mild to moderate symptoms.
On average, 70% of all people with a general anxiety disorder will consult with more than 10 physicians before the cause of their symptoms is accurately diagnosed. A recent study at Harvard Medical School reported that patients who cope poorly with stress become ill four times more often than those with good coping skills.
If you are not sure if you suffer from a general anxiety disorder, the following is a list of the most frequent signs of anxiety. They are: trembling, rapid heartbeat, lump in throat, frozen smile, neckaches, indigestion, insomnia, overeating, preoccupation with illness, fear of embarrassment or rejection, and fear of being ugly or fat.
Have you ever experienced any of these? If so, don’t worry. We all go through stress at some point in our lives. As long as you don’t have these feelings on a daily or weekly basis, you are probably fine. If you do experience a good portion of these signs of anxiety, read through the list below for strategies to developing inner peace.
Movement- Physical activity helps to reduce stress and anxiety. Walking is especially good for anxiety. Try not to push yourself to the point where it’s unpleasant…if you are straining or pushing yourself to hard, it will not be as beneficial in reducing anxiety.
Relax- Scientific studies have demonstrated that when viewing natural landscapes (sky, trees, greenery, water or flowers) people tend to feel more relaxed and less anxious. Remember, you deserve to enjoy your life and there is no reason to feel guilty about relaxing!
Eat right- It is important to eat a balanced diet rich in fruits, vegetables and whole grains. Balancing the diet helps to balance the levels of neurotransmitters involved in keeping stress and depression in check.
Take charge- A major cause of anxiety is the feeling of a lack of control. Helplessness is a huge component in depression and anxiety. It is a good idea to ask yourself questions like, “Why am I doing this?” or “Do I have to do this?” or “Will the world end if I don’t?” Most importantly, don’t be afraid to say “no” if you don’t feel comfortable doing something.
Take inventory on what causes you anxiety. Take the anxiety test I found in natural health magazine below.
0= no anxiety
1= mild anxiety
2= moderate anxiety
3= severe anxiety read more

Dealing with social anxiety

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A situation that defines and leads to social anxiety; misconceptions on the disorder; being shy and how it is as a main factor on feeling socially anxious; factors on the probable causes of social anxiety; how anxiety medication can help; how a person can help himself without use of prescription drugs.

Social anxiety, Anxiety medication

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A speech in front of a hundred people…. but an audience of millions watching on national television. Sounds scary right? Absolutely. It is not an exaggeration to say that there are so many people who are totally terrified of standing in front of a crowd. read more